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Do Large Clinical Trials Adequately Consider Individual Patient Physiology? Debating The RELIEF Study

By Michael Keane, BMBS, FANZCA and Shashikanth Manikappa, MD, DNB, FANZCA
February 21, 2019

Patient safety requires a well-informed debate about the rationale of large, randomized controlled trials (RCTs) and whether, by their very nature, they can adequately consider the unique physiology of every individual patient. 

Games Workshop Warhammer Fantasy Collectors Rule book Oop Rare In Box NewWarhammer Age of Sigmar Vampire Counts Abhorrant Ghoul King Royal Terrorgheist 2Warhammer 40k - Shadowspear - Daemonkin Chaos Space Marines Army (16 Models)  Continue reading “Do Large Clinical Trials Adequately Consider Individual Patient Physiology? Debating The RELIEF Study”

WAKE-UP Time for Thrombolysis in Acute Stroke?

Games Workshop Warhammer Age of Sigmar Chaos Knights

By Martina McGrath, MD
October 30, 2018

MRI thrombolysis for stroke of unknown time of onset

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Prior studies have suggested a particular pattern may be seen on an MRI of the brain in the early hours following stroke onset; a visible ischemic lesion on diffusion-weighted imaging along with the lack of a hyperintense signal in the same area on fluid-attenuated inversion recovery (FLAIR). The benefit of aggressive stroke intervention in patients with the combination of unknown time of symptom onset and this particular signal mismatch on MRI brain scans is unknown. Continue reading “WAKE-UP Time for Thrombolysis in Acute Stroke?”

GRENADIER Stone Giant G-2 white metal fantasy figure

By Olivier Lucar
October 16, 2018

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Wild West Exodus Red Oak Saloon

By Connor Emdin
September 26, 2018

15mm Vietnam War KELLEY’S HEROES Army Set inc 3 Boats VUSBX11 FoW 60946510gsm Vinyl 4x4' Frozen Planet Gaming Mat - Ideal for WarhammerPro Painted Reaper Miniatures Pathfinder – Almah, Merchant Princess- Fantasy RPGWarhammer Age of Sigmar Nighthaunt Vampire Counts Skeletons Skeleton Warriors 1 Continue reading “Use of Guideline-Recommended Medical Therapy in Patients with Heart Failure”

Restrictive versus Liberal Fluid Therapy in Abdominal Surgery

By Connor Emdin
August 28, 2018

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Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?

By Martina McGrath, MD
August 8, 2018

It is estimated that 1 in every 7.5 people in the US will die of sudden cardiac death.Shadowrun RPG - Sixth World Tared Deluxe Survival following out-of-hospital cardiac arrest has increased in recent years, from 10.2% in 2006, to 12.4% in 2015.1 However, only 9% of those surviving to hospital discharge were classified as having good functional status. Therefore, significant long-term neurologic impairment is a common outcome of cardiac arrest. Continue reading “Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?”

Cervical Cancer Screening Using HPV Testing Alone: Are We There Yet?

Fantasy AGE Role Playing Game - Bestiary

By Martina McGrath, MD
July 18, 2018

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Nurgle Metal Daemon Prince Unclean Very Well Painted One Great nyrupp3774-WFB Miniatures

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Dulaglutide in Type 2 Diabetes: Do GLP-1 agonists delay progression of diabetic nephropathy?

Advanced Race Guide For Pathfinder Role Playing Game - Hardcover Book

By Connor Emdin
June 27, 2018

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Procalcitonin-Guided Antibiotic Therapy in Lower Respiratory Tract Infection: Is It Safe?

DEEP DUNGEON Kanzen Hisshoubon Guide Famicom Book JI07

By Martina McGrath, MD
June 5, 2018

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TUNNELS & TROLLS, SUPPLEMENTS & ADD-ONS, MULTI-LISTING

By Lea Borgi, MD
May 16, 2018

25mm classical greek - heavy 12 figures - cav (24704)Star wars legion imperial Royal guard pro painted made to orderORDER OF BATTLES OF DIVISIONS - VOLUME 1 - PARTS 1, 2a, 2b and 3a - REPRINT Continue reading “Does Menu Labeling Lead to Healthier Food Choices?”