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Do Large Clinical Trials Adequately Consider Individual Patient Physiology? Debating The RELIEF Study

By Michael Keane, BMBS, FANZCA and Shashikanth Manikappa, MD, DNB, FANZCA
February 21, 2019

Patient safety requires a well-informed debate about the rationale of large, randomized controlled trials (RCTs) and whether, by their very nature, they can adequately consider the unique physiology of every individual patient. 

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WAKE-UP Time for Thrombolysis in Acute Stroke?

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By Martina McGrath, MD
October 30, 2018

MRI thrombolysis for stroke of unknown time of onset

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Prior studies have suggested a particular pattern may be seen on an MRI of the brain in the early hours following stroke onset; a visible ischemic lesion on diffusion-weighted imaging along with the lack of a hyperintense signal in the same area on fluid-attenuated inversion recovery (FLAIR). The benefit of aggressive stroke intervention in patients with the combination of unknown time of symptom onset and this particular signal mismatch on MRI brain scans is unknown. Continue reading “WAKE-UP Time for Thrombolysis in Acute Stroke?” →

10mm napoleonic DUTCH infantry 1807-1810 56 and 8 com 64 AS 4 th regt BY M M

By Olivier Lucar
October 16, 2018

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ROLEMASTER CREATURES & TREASURES II 2 - I.C.E. IRON CROWN RPG SHADOW WORLD MERP

By Connor Emdin
September 26, 2018

15mm ACW confederate - regiment 40 figures - inf (23930)15mm ACW confederate - regiment 32 figures - inf (32834)Citadel Miniatures Games Workshop Chronicle CM9 Hobgoblins Pre Slotta Metal Lot28mm WW2 Soviet KV-2 Heavy Tank Painted to a Professional Standard Continue reading “Use of Guideline-Recommended Medical Therapy in Patients with Heart Failure” →

Restrictive versus Liberal Fluid Therapy in Abdominal Surgery

By Connor Emdin
August 28, 2018

15mm ACW confederate - american civil war small infantry 36 figs - inf (21214)Star Wars X-Wing 2.0 Scum and Villainy Conversion Kit1985 ADD69 Githyanki P3 V3 Advanced Dungeons & Dragons Games Workshop AD&D GithLotr warhammer Metal - Ring Wraith Shadow Lord Foot & Mounted Continue reading “Restrictive versus Liberal Fluid Therapy in Abdominal Surgery” →

Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?

By Martina McGrath, MD
August 8, 2018

It is estimated that 1 in every 7.5 people in the US will die of sudden cardiac death.WWG Industry of War Full Resin Kit – 28mm Wargaming Terrain Model Diorama Survival following out-of-hospital cardiac arrest has increased in recent years, from 10.2% in 2006, to 12.4% in 2015.1 However, only 9% of those surviving to hospital discharge were classified as having good functional status. Therefore, significant long-term neurologic impairment is a common outcome of cardiac arrest. Continue reading “Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?” →

Cervical Cancer Screening Using HPV Testing Alone: Are We There Yet?

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By Martina McGrath, MD
July 18, 2018

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Vac man-Cap Toys- (stretch Good Condition-boxed Instruction Armstrong)-very With nyrupp1974-Other Vintage & Classic Toys

Item specifics

Condition:
Used: An item that has been previously used. See the seller’s listing for full details and description of ... Read moreabout the condition
 Brand: Stretch Armstrong

Dulaglutide in Type 2 Diabetes: Do GLP-1 agonists delay progression of diabetic nephropathy?

25mm roman era roman - legionaries 20 figs - inf (10730)

By Connor Emdin
June 27, 2018

World at War Magazine - Issue 62 - Spanish Civil War BattlesSword & Sorcery Trouble At Durbenford - Location and Campaign Sourcebook SealedT-72 Tank Company Battlefront Miniatures TSBX01 Brand New in BoxBOLT ACTION Segunda edición española - WARLORD GAMES - WORLD WAR II 25mm renaissance tartar - tartar cavalry 12 cavalry - cav (13100)

Procalcitonin-Guided Antibiotic Therapy in Lower Respiratory Tract Infection: Is It Safe?

15mm napoleonic french - 15 hussars - cav (90454)

By Martina McGrath, MD
June 5, 2018

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Games Workshop Warhammer Age of Sigmar Stormcast Eternals Lord-Aquilor

By Lea Borgi, MD
May 16, 2018

Honeybake Pots and Pans SetLord of the Rings Eowyn to Base and Mounted Games Workshop Middle Earth ÉowynWarlord Games German Africa Corps 28mm German Germany WWII Bolt Action Continue reading “Does Menu Labeling Lead to Healthier Food Choices?” →