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Do Large Clinical Trials Adequately Consider Individual Patient Physiology? Debating The RELIEF Study

By Michael Keane, BMBS, FANZCA and Shashikanth Manikappa, MD, DNB, FANZCA
February 21, 2019

Patient safety requires a well-informed debate about the rationale of large, randomized controlled trials (RCTs) and whether, by their very nature, they can adequately consider the unique physiology of every individual patient. 

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WAKE-UP Time for Thrombolysis in Acute Stroke?

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By Martina McGrath, MD
October 30, 2018

MRI thrombolysis for stroke of unknown time of onset

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Prior studies have suggested a particular pattern may be seen on an MRI of the brain in the early hours following stroke onset; a visible ischemic lesion on diffusion-weighted imaging along with the lack of a hyperintense signal in the same area on fluid-attenuated inversion recovery (FLAIR). The benefit of aggressive stroke intervention in patients with the combination of unknown time of symptom onset and this particular signal mismatch on MRI brain scans is unknown. Continue reading “WAKE-UP Time for Thrombolysis in Acute Stroke?”


By Olivier Lucar
October 16, 2018

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By Connor Emdin
September 26, 2018

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Restrictive versus Liberal Fluid Therapy in Abdominal Surgery

By Connor Emdin
August 28, 2018

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Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?

By Martina McGrath, MD
August 8, 2018

It is estimated that 1 in every 7.5 people in the US will die of sudden cardiac death.LEGO INSTRUCTIONS ONLY FOR LOTR 9474 HELMS DEEP Survival following out-of-hospital cardiac arrest has increased in recent years, from 10.2% in 2006, to 12.4% in 2015.1 However, only 9% of those surviving to hospital discharge were classified as having good functional status. Therefore, significant long-term neurologic impairment is a common outcome of cardiac arrest. Continue reading “Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?”

Cervical Cancer Screening Using HPV Testing Alone: Are We There Yet?

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By Martina McGrath, MD
July 18, 2018

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Vintage Team, Highway Rig (5580) Model LEGO nyrfav1974-LEGO Complete Sets & Packs

Item specifics

Used: An item that has been previously used. See the seller’s listing for full details and description of ... Read moreabout the condition
Brand: Lego
Model Theme: Model Team LEGO Set Name: Truck
Part Type: Box Sets LEGO Set Number: 5580
Features: Vintage LEGO Theme: Model Team
Packaging: Box Product Line (LEGO Theme): Model Team

Dulaglutide in Type 2 Diabetes: Do GLP-1 agonists delay progression of diabetic nephropathy?

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By Connor Emdin
June 27, 2018

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Procalcitonin-Guided Antibiotic Therapy in Lower Respiratory Tract Infection: Is It Safe?

LEGO Star Wars 75145 Eclipse Fighter - Brand New & Sealed

By Martina McGrath, MD
June 5, 2018

Lego Star Wars&Droid Gunship&Set - 75233Retired & Rare Lego 41317 Friends Catamaran Brand New and Sealed. Lego 60086 CITY Police Starter Set, NEW and Factory Sealed.

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LEGO Toy Story 3 Trash Compactor Escape (7596) - BNIB - Retired Set

By Lea Borgi, MD
May 16, 2018

Lego Speed Champions 75899 LaFerrari Brand New Sealed. Retired Set. Box V Good LEGO City Police 60068 Crooks HideoutLEGO Star Wars 7749 Echo Base TM Continue reading “Does Menu Labeling Lead to Healthier Food Choices?”