Do Large Clinical Trials Adequately Consider Individual Patient Physiology? Debating The RELIEF Study

By Michael Keane, BMBS, FANZCA and Shashikanth Manikappa, MD, DNB, FANZCA
February 21, 2019

Patient safety requires a well-informed debate about the rationale of large, randomized controlled trials (RCTs) and whether, by their very nature, they can adequately consider the unique physiology of every individual patient. 

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WAKE-UP Time for Thrombolysis in Acute Stroke?


By Martina McGrath, MD
October 30, 2018

MRI thrombolysis for stroke of unknown time of onset

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Prior studies have suggested a particular pattern may be seen on an MRI of the brain in the early hours following stroke onset; a visible ischemic lesion on diffusion-weighted imaging along with the lack of a hyperintense signal in the same area on fluid-attenuated inversion recovery (FLAIR). The benefit of aggressive stroke intervention in patients with the combination of unknown time of symptom onset and this particular signal mismatch on MRI brain scans is unknown. Continue reading “WAKE-UP Time for Thrombolysis in Acute Stroke?”

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By Olivier Lucar
October 16, 2018

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By Connor Emdin
September 26, 2018

Dinky Jaguar XK120 - Red - B NBROS Fendt 722 Tractor with DUALS 1 32 Scale Boxed NEW limited editionHOBBYMASTER HA2403 1 72 MIG-15 BIS USAF 7616Dinky No.130 Ford Consul Corsair - Red Metallic - Boxed Continue reading “Use of Guideline-Recommended Medical Therapy in Patients with Heart Failure”

Restrictive versus Liberal Fluid Therapy in Abdominal Surgery

By Connor Emdin
August 28, 2018

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Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?

By Martina McGrath, MD
August 8, 2018

It is estimated that 1 in every 7.5 people in the US will die of sudden cardiac death.Bmw 6-Series M6 Gt3 Rowe Racing Fia Gt World Cup Macau 2016 SPARK 1 43 SA149 Survival following out-of-hospital cardiac arrest has increased in recent years, from 10.2% in 2006, to 12.4% in 2015.1 However, only 9% of those surviving to hospital discharge were classified as having good functional status. Therefore, significant long-term neurologic impairment is a common outcome of cardiac arrest. Continue reading “Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?”

Cervical Cancer Screening Using HPV Testing Alone: Are We There Yet?


By Martina McGrath, MD
July 18, 2018

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Item specifics

Used: An item that has been previously used. See the seller’s listing for full details and description of ... Read moreabout the condition
Brand: Dinky
Packaging: None/ Loose MPN: 38b
Series: Cars Scale: 1:43
Year of Manufacture: 1947-49 Material: DieCast, Plastic
Vehicle Type: Car Convertable Country/Region of Manufacture: United Kingdom
Vehicle Make: Sunbeam Type: Car - Passenger
Colour: Yellow & Fawn Sub-Type: Sunbeam

Dulaglutide in Type 2 Diabetes: Do GLP-1 agonists delay progression of diabetic nephropathy?

Porsche 911 RSR no.88 3rd LM GTE AM LEMANS 2016 ( K. Al Qubaisi - D.Heinemeier H

By Connor Emdin
June 27, 2018

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Procalcitonin-Guided Antibiotic Therapy in Lower Respiratory Tract Infection: Is It Safe?

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By Martina McGrath, MD
June 5, 2018

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1 18 Datsun 240Z 2.4 Litre Straight Six Nissan Fairlady S30 GTR Nismo 370 GT

By Lea Borgi, MD
May 16, 2018

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