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Do Large Clinical Trials Adequately Consider Individual Patient Physiology? Debating The RELIEF Study

By Michael Keane, BMBS, FANZCA and Shashikanth Manikappa, MD, DNB, FANZCA
February 21, 2019

Patient safety requires a well-informed debate about the rationale of large, randomized controlled trials (RCTs) and whether, by their very nature, they can adequately consider the unique physiology of every individual patient. 

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WAKE-UP Time for Thrombolysis in Acute Stroke?


By Martina McGrath, MD
October 30, 2018

MRI thrombolysis for stroke of unknown time of onset

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Prior studies have suggested a particular pattern may be seen on an MRI of the brain in the early hours following stroke onset; a visible ischemic lesion on diffusion-weighted imaging along with the lack of a hyperintense signal in the same area on fluid-attenuated inversion recovery (FLAIR). The benefit of aggressive stroke intervention in patients with the combination of unknown time of symptom onset and this particular signal mismatch on MRI brain scans is unknown. Continue reading “WAKE-UP Time for Thrombolysis in Acute Stroke?”

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By Olivier Lucar
October 16, 2018

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FORD SIERRA RS Cosworth no. 6 Winner Rally 24 H Acids Van Ieper 1989

By Connor Emdin
September 26, 2018

1 43 Subaru Legacy RS Rally New Zealand 1993 Colin McRae hpi-racingMaisto 1 18 Scale Diecast 38134 - 2017 Ford GT - blueeUniversal Hobbies 1 16th Scale Tractor FORDSON DEXTA ( 1957 ) Launch EditionDINKY TOYS 163 BRISTOL 450 SPORTS COUPE - VNMB Continue reading “Use of Guideline-Recommended Medical Therapy in Patients with Heart Failure”

Restrictive versus Liberal Fluid Therapy in Abdominal Surgery

By Connor Emdin
August 28, 2018

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Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?

By Martina McGrath, MD
August 8, 2018

It is estimated that 1 in every 7.5 people in the US will die of sudden cardiac death.Corgi Toys 233 Heinkel Bubble Car orange Original VNMB Survival following out-of-hospital cardiac arrest has increased in recent years, from 10.2% in 2006, to 12.4% in 2015.1 However, only 9% of those surviving to hospital discharge were classified as having good functional status. Therefore, significant long-term neurologic impairment is a common outcome of cardiac arrest. Continue reading “Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?”

Cervical Cancer Screening Using HPV Testing Alone: Are We There Yet?

Phoenix 1 400 Thai Airways Airbus A330-300 HS-TEO (PH10444) Die-Cast Model Plane

By Martina McGrath, MD
July 18, 2018

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HOT WHEELS 1 18 X5524 FF - RED FERRARI - nykhxw5774-Contemporary Manufacture

Item specifics

Condition: Used :
An item that has been previously used. See the seller’s listing for full details and description of any imperfections.See all condition definitions- opens in a new window or tab
Seller notes: The Model Is In Mint Condition The Box Is In Near Mint Condition - V. Slightly Worn
Brand: HOT WHEELS Scale: 18
MPN: CARMTOYS13629 EAN: Does not apply

Dulaglutide in Type 2 Diabetes: Do GLP-1 agonists delay progression of diabetic nephropathy?

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By Connor Emdin
June 27, 2018

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Procalcitonin-Guided Antibiotic Therapy in Lower Respiratory Tract Infection: Is It Safe?

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By Martina McGrath, MD
June 5, 2018

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By Lea Borgi, MD
May 16, 2018

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